wfnref

WFN References

Last Updated: 3 April 2012

Bergstrand M, Hooker AC, Wallin JE, Karlsson MO. Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models. AAPS J. 2011;13(2):143-51.

Hauser RA, Holford NHG. Quantitative Description of Loss of Clinical Benefit Following Withdrawal of Levodopa–Carbidopa and Bromocriptine in Early Parkinson’s Disease. Movement Disorders 2002; 17:961-968

Holford NHG, Black P, Briant R, Couch R, Kennedy J. Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial. Clinical Pharmacokinetics 1993a; 25:495-505

Holford NHG, Hashimoto Y, Sheiner LB. Time and theophylline concentration help explain the recovery of peak flow following acute airways obstruction. Population analysis of a randomised concentration-controlled trial. Clinical Pharmacokinetics 1993b; 25:506-515

Holford NHG, Peace KE. Results and validation of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine. Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11471-11475

Jonsson N, Karlsson MO. Xpose 2. A population analysis model building aid. 1997

Jonsson EN, Karlsson MO. Automated covariate model building within NONMEM. Pharm Res 1998 Sep;15(9):1463-8

Mandema JW, Verotta D, Sheiner LB. Building population pharmacokinetic-pharmacodynamic models. I. models for covariate effects. J. Pharmacokin. Biopharm. 1992; 20: 511-528

Parke J, Holford NHG, Charles BC. A procedure for generating bootstrap samples for the validation of nonlinear mixed-effect population models. Computer Methods and Programs in Biomedicine 1999; 59:19-29